Perioral Lines Filler

Smooth away the signs of ageing with our Perioral Lines Filler. This targeted treatment reduces wrinkles around the mouth, restoring a youthful, vibrant look. Our approach ensures a subtle enhancement, maintaining your natural beauty and expression. Get subtle yet transformative and effective results.

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Perioral lines filler is a dermal filler for wrinkles around the mouth. Filler for lip lines can be made from various substances; currently, hyaluronic acid (HA) filler is the most popular dermal filler due to a very low rate of associated complications. At Harley Street MD in London, we use FDA-approved Allergan HA filler for lip lines and other aesthetic treatments. 

What are Perioral Lines and Wrinkles?

Perioral lines and wrinkles are the lines around our mouths that can create facial expressions that give the impression of being annoyed or sad. As we age, loss of collagen and reduced tone of the orbicularis oris muscle can lead to the appearance of perioral or “smoker’s lines”. 

As you age, there will be a loss of facial volume and the slowing down of collagen and elastin production — which is critical for good skin tone. This can cause perioral lines and wrinkles to become deeper and more noticeable. Smoking/vaping, as well as other factors, such as high UV exposure, can also contribute to wrinkles around the mouth area. The changes you may notice are: 

  • Oral commissures — The corners of the mouth where the upper and lower lips meet start to “turn down”.
  • Marionette lines — The lines from the corners of the mouth down to the bottom of the chin become deeper.
  • Perioral “smokers” lines — Fine lines from above the lip.

How to Get Rid of Lines around the Mouth

Dermal fillers can help to get rid of lines around the mouth by rejuvenating and smoothing skin to achieve a more youthful appearance — without needing cosmetic surgery. Dermal fillers can also be used following a facelift to delay the natural progression of ageing, which will still happen.

HA dermal fillers can totally transform your overall appearance by: 

  • Restoring loss of volume
  • Providing structural support to lift up oral commissures
  • Fill deep creases caused by marionette lines
  • Smooth out fine perioral lines. 

Treatment with dermal fillers replenishes lost volume and stimulates natural hyaluronic acid and collagen production. You will be amazed at the difference it makes by softening those wrinkles around your mouth and restoring the corners of your mouth to their previous state.

At our Harley Street London clinic, we often combine it with other treatments, such as smile line filler, tear trough treatment, and Botox injections, to help you achieve a more youthful, rejuvenated appearance without the risks associated with cosmetic surgery.

Perioral Lines Treatment — Before and After Photos

peri-oral lines before and after

What Is the Best Treatment for Perioral Lines?

At our Harley Street aesthetic clinic in London, Dr Chia Tan recommends the Juvederm Vycross range of HA fillers as the best treatment for perioral lines. Produced by Allergan, Juvederm is the most popular brand of hyaluronic acid-based fillers in the world. Results generally last between 12 and 18 months, with most clients choosing to have an annual treatment to soften the appearance of fine lines in the perioral area and maintain a youthful look. 

Why Choose Harley Street MD Clinic in London?

All non-surgical aesthetic treatments carry potential risks and complications. By selecting a medically qualified and trained aesthetics expert with extensive anatomy knowledge, these can be significantly reduced. 

One of the few aesthetic clinics in the UK with CQC-registration, Harley Street MD in London was started by Dr Chia Tan.. Renowned aesthetic physician Dr Tan has a Diploma in Otolaryngology-Head and Neck Surgery (DOHNS) and has a full registration with the GMC. Dr Tan is also a member of the following groups:

All our filler and injectable treatments are performed by Dr Tan. With minimal downtime, this treatment is an extremely effective, quick way to look rejuvenated in under half an hour. 

Book a free, no-obligation consultation with Harley Street MD at our central London aesthetic clinic. We’ll discuss your concerns and treatment options to help you achieve the results you want.

About Your Treatment

Your treatment

  • PROCEDURE TIME 30-45 minutes

  • BACK TO WORK Same day


  • FULL RECOVERY 1-2 days

  • DURATION OF RESULT 9-12 months

  • RESULTS Immediate

Treatment price

Perioral line
from  £350

More information

Prior to your treatment, avoid:

Non-steroidal anti-inflammatory (NSAIDs) medicine for two days (e.g. ibuprofen, diclofenac)
Vitamin E, Ginkgo Biloba for two days
Alcohol for one day
Aspirin for seven days (if you take aspirin for medical reasons, please consult your doctor).
Your skin will be cleansed and disinfected.
Topical numbing cream will be used to ensure comfort; this takes about 5 to 10 minutes to work.
Local anaesthetic is integrated within all the dermal fillers used to further minimise any discomfort during and after the procedure.
An ice pack or arnica can be used to minimise bruising.
The procedure takes around 30 minutes, on average.
Results are pretty immediate, with minimum or no downtime at all.
This treatment is not suitable if you are:
Pregnant or breastfeeding
Have a known hypersensitivity to dermal fillers
In the presence of infection or severe inflammation at the injection sites (e.g. cold sores).
Following your treatment, you can expect the following:

Mild bruising, but this usually fades quickly (you can minimise bruising by avoiding the aforementioned medication before the procedure).
Mild swelling, which usually subsides within two days.
Cold sore flare-up (please discuss with your doctors regarding prophylactics antiviral medication before treatments).

Complications such as local infection are rare (please adhere to the post-treatment advice to avoid infection; antibiotics might be needed in such cases).

You can carry on with your day pretty much as usual immediately after leaving the clinic; however, please make note of the following things to avoid:

Following your treatment, avoid the following:
Using any products on your face and lips for at least four hours after treatment
Using skincare with peeling chemicals for two days (e.g. glycolic acid)
Strenuous exercise for two days
Alcohol for two days
Sun tanning/sauna/extreme heat for two weeks.

Always protect your skin with SPF 50 sunscreen the day after treatment, and we recommend applying sun protection if you are spending time outdoors.

Concurrent treatment such as laser skin resurfacing, microdermabrasion or chemical peels should not be performed for at least one week following dermal fillers.

Don’t forget to book your complimentary follow-up consultation in two weeks’ time to review your progress,

Get a Free Aesthetic Treatment Consultation

Get in touch for your consultation with one of our team of professionals.

What People Are Saying

A.O – Highbury

The venesection was painless to say the least, thank you for using local anaesthetics; highly recommended

J.H – Romford

‘I blast and cruise for years. When my haematocrit level went up, my GP did not seem to care and I couldn’t possibly wait for weeks to see a specialist. I am so lucky that to have found Harley Street MD through my research and it is the only clinic I have found that accept self-referral for therapeutic venesection due to AAS use.

Y.R – Vauxhall

I was recommended by my gym mate, I can’t thank you enough for sorting out my prolactin issue due to steroid use. You are a godsend.

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